Rapid detection of thioredoxin reductase with a fluorescent probe <i>via</i> a Tag-Sec method
Junyan Ma, Yaoyu Xu, Zhao We, Beibei Wang, Chunhuan Zhang, Zhenxing Zhang
Abstract
A Tag-Sec fluorescent probe was designed that could detect both thioredoxin reductase and selenocysteine with high sensitivity, selectivity, broad pH tolerance and good water solubility.
Topics & Concepts
Thioredoxin reductaseFluorescenceThioredoxinChemistrySelectivitySelenocysteineReductaseSolubilityBiochemistryCombinatorial chemistryEnzymeOrganic chemistryCysteineOpticsPhysicsCatalysisRedox biology and oxidative stressSulfur Compounds in BiologySelenium in Biological Systems