Rehmannioside A improves cognitive impairment and alleviates ferroptosis via activating PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway after ischemia
Chen Fu, Yifan Wu, Shaojiao Liu, Chaoqin Luo, Yu-Qiao Lu, Menghan Liu, Ling‐Feng Wang, Zhang Yunling, Xuemei Liu
Topics & Concepts
Glutathione peroxidaseMorris water navigation taskPharmacologyPI3K/AKT/mTOR pathwayMyeloperoxidaseGlutathioneChemistrySuperoxide dismutaseMedicineProtein kinase BNicotinamide adenine dinucleotide phosphateOxidative stressBiochemistryEndocrinologyInternal medicineApoptosisHippocampusInflammationOxidase testEnzymeFerroptosis and cancer prognosisImmune cells in cancerNeuroinflammation and Neurodegeneration Mechanisms