Mutations in <i>troABCD</i> against Copper Overload in a <i>copA</i> Mutant of Streptococcus suis
Xia Yang, Wei Peng, Yanna Wang, Kang Yan, Zewen Liu, Ting Gao, Keli Yang, Wei Liu, Rui Guo, Chang Li, Huanchun Chen, Yongxiang Tian, Danna Zhou, Weicheng Bei, Fangyan Yuan
Abstract
deletion mutant strain in the presence of high concentrations of copper and accumulated less copper. These findings are consistent with a model wherein defective TroABCD resulted in decreased cellular accumulation of copper and protected the strain against copper poisoning.
Topics & Concepts
MutantHomeostasisBiologyMicrobiologyGeneIntracellularGeneticsCell biologyTrace Elements in HealthStreptococcal Infections and TreatmentsAntimicrobial Resistance in Staphylococcus