Smart Nanoarchitectures for Precision RNA Delivery: Harnessing Endogenous and Exogenous Stimuli in Cancer Treatment
Jintao Hao, Yue Li, Xuhui Huang, Nannan Qi, Yanan Sun, Chaoxing He, Shaokun Yang, Zhi-Yun Niu, Xian Qi, Bai Xiang
Abstract
, pH, redox potential, enzyme, light, magnetic fields, and ultrasound), enabling targeted delivery and controlled RNA release. This review highlights recent advances in the design and mechanisms of stimuli-responsive RNA nanocarriers, emphasizing key research findings and exploring future perspectives for their clinical translation.
Topics & Concepts
EndogenyRNACancerNanotechnologyComputational biologyNeuroscienceChemistryCell biologyMedicineComputer scienceBiologyMaterials scienceBiochemistryInternal medicineGeneRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesMicroRNA in disease regulation