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Efficacy and side effects of Sputnik V, Sinopharm and AstraZeneca vaccines to stop COVID-19; a review and discussion

Nasrin Ghiasi, Rohollah Valizadeh, Mohammad Arabsorkhi, Tahere Sadat Hoseyni, Korosh Esfandiari, Tella Sadighpour, Hamid Reza Jahantigh

2021Immunopathologia Persa91 citationsDOIOpen Access PDF

Abstract

We believe that vaccination is just a way to eliminate or strongly stop the COVID-19. In this regard, there are several vaccines with different efficacy and side effects. It is urgently required to have some efficient vaccines for the prevention and control of SARS-CoV-2. In this review, international databases were considered for searching relevant articles from 1 January 2020 to 1 May 2021. Keywords were COVID-19, novel coronavirus, 2019- nCoV, coronavirus disease 2019, vaccine, Sputnik V, Gamaleya, Gam-COVID-Vac, Sinopharm, BBIBP-CorV, AstraZeneca, Vaxzevria, Oxford, ChAdOx1 nCoV-19 and AZD1222. Three Sputnik V, Sinopharm and AstraZeneca vaccines are useful to gain herd immunity. Enough intervals (at least three weeks/21 days) must be considered for sufficient neutralizing antibody titers. What is important is that the vaccination should be accelerated with each of the aforementioned three vaccines to achieve herd immunity in a shorter period of time because all three vaccines provide 100% prevention of severe COVID-19.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Herd immunityVaccinationMedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakImmunityVirologyCoronavirusImmunologyDiseaseImmune systemInfectious disease (medical specialty)Internal medicineOutbreakSARS-CoV-2 and COVID-19 ResearchVaccine Coverage and HesitancyImmune responses and vaccinations