<i>Lactobacillus crispatus</i>-derived exopolysaccharides with antibacterial activity limit <i>Salmonella typhimurium</i> invasion by inhibiting inflammasome-mediated pyroptosis
Chenchen Ding, Huixian Wu, Xiuyun Cao, Zhangshan Gao, Zhihui Tang, Wentao Fan, Liping Yan, Bin Liu, Hong Lin, Suquan Song
Abstract
induced pyroptosis, with the mechanism that EPS 7-4 affects ASC oligomerization during inflammasome-mediated pyroptosis. Therefore, due to its excellent anti-bacterial and anti-inflammatory abilities, EPS 7-4 is a promising health regulator owing to its excellent antibacterial and anti-inflammatory abilities.
Topics & Concepts
PyroptosisMicrobiologyInflammasomeSalmonellaBiofilmLactobacillus crispatusLactobacillusVirulenceChemistryBiologyBacteriaInflammationGeneBiochemistryImmunologyGeneticsInflammasome and immune disordersImmune Response and InflammationStreptococcal Infections and Treatments