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Single-cell atlas of human liver development reveals pathways directing hepatic cell fates

Brandon T. Wesley, Alexander Ross, Daniele Muraro, Zhichao Miao, Sarah H. Saxton, Rute A. Tomaz, Carola Maria Morell, Katherine Ridley, Ekaterini D. Zacharis, Sandra Petrus-Reurer, Judith Kraiczy, Krishnaa T. Mahbubani, Stephanie Brown, José Garcia‐Bernardo, Clara Alsinet, Daniel J. Gaffney, Dave Horsfall, Olivia Tysoe, Rachel A. Botting, Emily Stephenson, Dorin-Mirel Popescu, Sonya A. MacParland, Gary D. Bader, Ian D. McGilvray, Daniel Ortmann, Fotios Sampaziotis, Kourosh Saeb‐Parsy, Muzlifah Haniffa, Kelly R. Stevens, Matthias Zilbauer, Sarah A. Teichmann, Ludovic Vallier

2022Nature Cell Biology138 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCell biologyInduced pluripotent stem cellCell typeCellCholangiocyteHepatocyteOrganoidOrganogenesisStem cellComputational biologyEmbryonic stem cellGeneticsGeneEndocrinologyIn vitroLiver physiology and pathologyRenal and related cancersSingle-cell and spatial transcriptomics