An ion transport switch based on light-responsive conformation-dependent G-quadruplex transmembrane channels
Chunying Li, Hui Chen, Xiaohai Yang, Kemin Wang, Jianbo Liu
Abstract
A light-responsive ion transport switch has been developed based on conformation-dependent azobenzene-incorporated lipophilic G-quadruplex channels, which provides a new smart approach for the selective transport of K + ions across the lipid membrane.
Topics & Concepts
AzobenzeneChemistryIon channelIon transporterIonBiophysicsMembraneTransmembrane proteinTransmembrane channelsVoltage-gated ion channelBiochemistryMoleculeReceptorOrganic chemistryBiologyPhotoreceptor and optogenetics researchMolecular Sensors and Ion DetectionAdvanced biosensing and bioanalysis techniques