Reducing state attenuates ectodomain shedding of GPVI while restoring adhesion capacities of stored platelets: evidence addressing the controversy around the effects of redox condition on thrombosis
Ehteramolsadat Hosseini, Amin Solouki, Zahra Oushyani Roudsari, Faranak Kargar, Mehran Ghasemzadeh
Topics & Concepts
GPVIPlateletIntegrinCell biologyPlatelet activationChemistryPlatelet adhesivenessEctodomainAdhesionCell adhesionThrombusPharmacologyImmunologyReceptorBiochemistryMedicineBiologyInternal medicinePlatelet aggregationOrganic chemistryPlatelet Disorders and TreatmentsVenous Thromboembolism Diagnosis and ManagementHeparin-Induced Thrombocytopenia and Thrombosis