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Revolutionizing MASLD: How Artificial Intelligence Is Shaping the Future of Liver Care

Nicola Pugliese, Arianna Bertazzoni, Cesare Hassan, Jörn M. Schattenberg, Alessio Aghemo

2025Cancers15 citationsDOIOpen Access PDF

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is emerging as a leading cause of chronic liver disease. In recent years, artificial intelligence (AI) has attracted significant attention in healthcare, particularly in diagnostics, patient management, and drug development, demonstrating immense potential for application and implementation. In the field of MASLD, substantial research has explored the application of AI in various areas, including patient counseling, improved patient stratification, enhanced diagnostic accuracy, drug development, and prognosis prediction. However, the integration of AI in hepatology is not without challenges. Key issues include data management and privacy, algorithmic bias, and the risk of AI-generated inaccuracies, commonly referred to as "hallucinations". This review aims to provide a comprehensive overview of the applications of AI in hepatology, with a focus on MASLD, highlighting both its transformative potential and its inherent limitations.

Topics & Concepts

Computer scienceArtificial liverData scienceMedicineLiver failureInternal medicineArtificial Intelligence in Healthcare and EducationCOVID-19 diagnosis using AIArtificial Intelligence in Healthcare
Revolutionizing MASLD: How Artificial Intelligence Is Shaping the Future of Liver Care | Litcius