Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer
J. Nathaniel Diehl, Priya S. Hibshman, Irem Ozkan‐Dagliyan, Craig M. Goodwin, Sarah V. Howard, Adrienne D. Cox, Channing J. Der
Topics & Concepts
KRASPancreatic cancerMAPK/ERK pathwayMutantProtein kinase ACancer researchKinaseMAPK cascadeMedicineBiologyCancerCell biologyInternal medicineBiochemistryGeneColorectal cancerMelanoma and MAPK PathwaysCancer Mechanisms and TherapyPI3K/AKT/mTOR signaling in cancer