Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways
Xiaotong Wang, Qianyi Gong, Changfeng Song, Jiaping Fang, Yun Yang, Xin Liang, Xuan Huang, Jianwen Liu
Topics & Concepts
BerberineCisplatinApoptosisProgrammed cell deathMAPK/ERK pathwayChemistryReactive oxygen speciesp38 mitogen-activated protein kinasesMTT assayCytotoxicityCaspasePhotodynamic therapyCancer researchPharmacologySignal transductionCell biologyBiologyBiochemistryIn vitroChemotherapyGeneticsOrganic chemistryPhotodynamic Therapy Research StudiesBerberine and alkaloids researchCancer therapeutics and mechanisms