Litcius/Paper detail

The Importance of Marine Omega-3s for Brain Development and the Prevention and Treatment of Behavior, Mood, and Other Brain Disorders

James J. DiNicolantonio, James H. O’Keefe

2020Nutrients144 citationsDOIOpen Access PDF

Abstract

Most of the global population is deficient in long-chain marine omega-3s. In particular, docosahexaenoic acid (DHA), a long-chain omega-3 fatty acid, is important for brain and eye development. Additionally, DHA plays a significant role in mental health throughout early childhood and even into adulthood. In the brain, DHA is important for cellular membrane fluidity, function and neurotransmitter release. Evidence indicates that a low intake of marine omega-3s increases the risk for numerous mental health issues, including Attention Deficit Hyperactivity Disorder (ADHD), autism, bipolar disorder, depression and suicidal ideation. Studies giving supplemental marine omega-3s have shown promise for improving numerous mental health conditions. This paper will review the evidence surrounding marine omega-3s and mental health conditions.

Topics & Concepts

Docosahexaenoic acidPsychiatryBipolar disorderMental healthMood disordersDepression (economics)MoodBrain developmentBrain functionSuicidal ideationOmega 3 fatty acidBrain Structure and FunctionPopulationPsychologyMedicineNeurosciencePoison controlInjury preventionBiologyPolyunsaturated fatty acidEnvironmental healthNeuroimagingAnxietyFatty acidBiochemistryEconomicsMacroeconomicsFatty Acid Research and HealthBirth, Development, and Health