Chasing perfection: validation and polishing strategies for telomere-to-telomere genome assemblies
Ann M. Mc Cartney, Kishwar Shafin, Michael Alonge, Andrey V. Bzikadze, Giulio Formenti, Arkarachai Fungtammasan, Kerstin Howe, Chirag Jain, Sergey Koren, Glennis A. Logsdon, Karen H. Miga, Alla Mikheenko, Benedict Paten, Alaina Shumate, Daniela C. Soto, Ivan Sović, Jonathan Wood, Justin M. Zook, Adam M. Phillippy, Arang Rhie
Topics & Concepts
Nanopore sequencingGenomeTelomereComputational biologySequence assemblyTandem repeatComputer sciencePolishingBiologyGeneticsDNAGeneEngineeringGene expressionMechanical engineeringTranscriptomeGenomics and Phylogenetic StudiesChromosomal and Genetic VariationsCRISPR and Genetic Engineering