Biocatalytic hydroxylation tertiary C-H bonds for synthesis of chiral tertiary alcohols by cytochrome P450
Ruyue Zhang, Ting Ma, Dan Liŭ, Yuli Yang, Luo Gao, Haibo Cui, Zhongqiang Wang, Yong‐Zheng Chen
Topics & Concepts
HydroxylationChemistryCatalysisEnantioselective synthesisCytochrome P450Substrate (aquarium)BiocatalysisMonooxygenaseMolecular oxygenTertiary alcoholsOrganic chemistryCombinatorial chemistryEnzymeReaction mechanismGeologyOceanographyPharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation MechanismsEnzyme Catalysis and Immobilization