Litcius/Paper detail

Transdermal delivery of timolol maleate using hydrogel microneedles for the treatment of infantile haemangiomas

Xiaokun Lin, Tongshuai Kuang, Lei Wang, Wei Cai, Linxing Yang, Changrong Guo, Xinyang Pan, Yuanhao Wang, Qiang Gao, Kaihui Nan, Lingli Li

2025Materials Today Bio7 citationsDOIOpen Access PDF

Abstract

studies on nude mice demonstrated that BSAMA-TIM-MNs inhibited the growth of haemangioma xenografts. Our TIM-delivering MNs exhibited high therapeutic efficacy, minimal cytotoxicity, and reduced dosing frequency. In conclusion, BSAMA-TIM MNs provide a promising strategy for treating IH.

Topics & Concepts

TransdermalTimololBiomedical engineeringMedicineMaterials sciencePharmacologySurgeryIntraocular pressureAdvancements in Transdermal Drug DeliveryVascular Malformations and HemangiomasOrbital Angular Momentum in Optics