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Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes

Jina Ko, Martin Wilkovitsch, Juhyun Oh, Rainer H. Köhler, Evangelia Bolli, Mikaël J. Pittet, Claudio Vinegoni, David B. Sykes, Hannes Mikula, Ralph Weissleder, Jonathan Carlson

2022Nature Biotechnology113 citationsDOIOpen Access PDF

Topics & Concepts

Bioorthogonal chemistryImmunofluorescenceFluorescenceFluorescent labellingCyclingChemistryCell biologyBiophysicsBiologyAntibodyImmunologyOpticsPhysicsHistoryCombinatorial chemistryArchaeologyClick chemistryAdvanced Biosensing Techniques and ApplicationsAdvanced biosensing and bioanalysis techniquesAdvanced Fluorescence Microscopy Techniques
Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes | Litcius