Modulation of Ca2+ signaling by antiapoptotic Bcl-2 versus Bcl-xL: From molecular mechanisms to relevance for cancer cell survival
Nicolas Rosa, Femke Speelman-Rooms, Jan B. Parys, Geert Bultynck
Topics & Concepts
Bcl-xLEndoplasmic reticulumBcl-2 familyCell biologyPumaApoptosisProgrammed cell deathContext (archaeology)IntracellularMitochondrionBiologyCancer cellInositol trisphosphate receptorInositolCalcium signalingSignal transductionReceptorCancerBiochemistryGeneticsPaleontologyCell death mechanisms and regulationAutophagy in Disease and TherapyCalpain Protease Function and Regulation