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Rosmarinic acid relieves LPS-induced sickness and depressive-like behaviors in mice by activating the BDNF/Nrf2 signaling and autophagy pathway

Yi Yu, Ye Li, Keming Qi, Wei Xu, Yicong Wei

2022Behavioural Brain Research35 citationsDOI

Topics & Concepts

NeuroinflammationWestern blotNeuroprotectionSickness behaviorBrain-derived neurotrophic factorAutophagyPharmacologyGCLCNeurotrophic factorsNissl bodyOxidative stressLipopolysaccharideChemistryMedicineImmunologyInflammationInternal medicineGlutathioneReceptorApoptosisBiochemistryStainingPathologyEnzymeGeneTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy
Rosmarinic acid relieves LPS-induced sickness and depressive-like behaviors in mice by activating the BDNF/Nrf2 signaling and autophagy pathway | Litcius