Antibacterial properties of main-chain cationic polymers prepared through amine–epoxy ‘Click’ polymerization
Junki Oh, Seung-Jin Kim, Min‐Kyu Oh, Anzar Khan
Abstract
) - a model organism to develop drugs against rapidly spreading tuberculosis (TB) infections. The hemolysis assay indicated that a majority of antimicrobial agents did not disrupt red blood cell membranes. The mechanistic studies suggested that cell wall disruption by the cationic polymers was the likely cause of bacterial death.
Topics & Concepts
Cationic polymerizationChemistryMycobacterium smegmatisPolymerizationPolymer chemistryPolymerAmine gas treatingCombinatorial chemistryOrganic chemistryMycobacterium tuberculosisTuberculosisPathologyMedicineAntimicrobial agents and applicationsClick Chemistry and ApplicationsChemical Synthesis and Analysis