Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases
Tianyuan Lu, Vincenzo Forgetta, J. Brent Richards, Celia M.T. Greenwood
Topics & Concepts
Exome sequencingDiseaseMedicineBiobankFamily historyPolygenic risk scoreGeneticsGenetic testingBiologyInternal medicineGenotypeMutationSingle-nucleotide polymorphismGeneGenetic Associations and EpidemiologyGenomics and Rare DiseasesBRCA gene mutations in cancer