Systematic evaluation of structure–property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride

Benjamin J. Buckley, Ashraf Aboelela, Hiwa Majed, Richard S. Bujaroski, Karen L. White, Andrew K. Powell, Wen Wang, Kasiram Katneni, Jessica Saunders, David M. Shackleford, Susan A. Charman, Gregory M. Cook, Michael J. Kelso, Marie Ranson