Controlled polysorbate 20 hydrolysis – A new approach to assess the impact of polysorbate 20 degradation on biopharmaceutical product quality in shortened time
Tobias Graf, Kathrin Abstiens, Frank Wedekind, Carsten Elger, Markus Haindl, Christine Wurth, Michael Leiß
Topics & Concepts
PolysorbateActive ingredientChemistryBiopharmaceuticalHydrolysisChromatographyPolyvinyl alcoholPulmonary surfactantSorbitanDegradation (telecommunications)Dosage formIngredientQuality by DesignOrganic chemistryBiochemistryParticle sizePharmacologyFatty acidBiotechnologyFatty acid esterComputer scienceFood scienceMedicinePhysical chemistryTelecommunicationsBiologyProtein purification and stabilityDrug Solubulity and Delivery SystemsSafe Handling of Antineoplastic Drugs