Pd(II)-Catalyzed Fujiwara–Moritani Reactions for the Synthesis and Functionalization of Substituted Coumarins
Verónica Ortiz‐de‐Elguea, Asier Carral‐Menoyo, Lorena Simón-Vidal, Mikel Martinez-Nunes, Iratxe Barbolla, Marta G. Lete, Nuria Sotomayor, Esther Lete
Abstract
cyclization led to 4-substituted coumarins in moderate yields. Selected examples have been further functionalized in C3 through a second intermolecular C-H alkenylation reaction to give coumarin-acrylate hybrids, whose fluorescence spectra have been measured.
Topics & Concepts
Surface modificationCatalysisChemistryCombinatorial chemistryCoumarinOrganic chemistryPhysical chemistryCatalytic C–H Functionalization MethodsSynthesis of Organic CompoundsSynthesis and Biological Evaluation