In Vitro Assessment of Transporter Mediated Perpetrator DDIs for Several Hepatitis C Virus Direct-Acting Antiviral Drugs and Prediction of DDIs with Statins Using Static Models
Xiaoyan Chu, Grace Chan, Robert Houle, Meihong Lin, Jocelyn Yabut, Christine Fandozzi
Topics & Concepts
PitavastatinRosuvastatinPharmacologyAtorvastatinPravastatinMultidrug resistance-associated protein 2DaclatasvirMedicineTransporterDrugADMEAtazanavirHepatitis C virusChemistryATP-binding cassette transporterVirologyInternal medicineCholesterolVirusViral loadRibavirinBiochemistryAntiretroviral therapyGeneDrug Transport and Resistance MechanismsHIV/AIDS drug development and treatmentHepatitis C virus research