Adverse Reactions of the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine in Healthcare Workers in Korea
Yun Woo Lee, So Yun Lim, Ji‐Hyang Lee, Joon Seo Lim, Miseo Kim, Seonhee Kwon, Jiyeon Joo, Sun Hee Kwak, Eun Ok Kim, Jiwon Jung, Hyouk‐Soo Kwon, Tae‐Bum Kim, Sung‐Han Kim, Seongman Bae
Abstract
= 0.006). The most common systemic reactions were muscle ache (69.1%), fatigue (65.7%), headache (48.7%), chills (44.2%), and fever (32.1%), and were notably more common after the second dose vaccine as well. We also noted a sex difference in which the frequency of adverse reactions after the second dose of the vaccine was significantly higher in females, which was not observed after the first dose. The rates of adverse reactions were lower in older age groups, and the rates and severities of the adverse reactions decreased during the 3-day period following vaccination.