A nationwide, multicentric case–Control study on vitiligo (MEDEC-V) to elicit the magnitude and correlates
Nilendu Sarma, Sayantani Chakraborty, Shital Poojary, BM Shashi Kumar, LalitKumar Gupta, Leelavathy Budamakuntla, Leishiwon Kumrah, Suchibrata Das, AjayGovindrao Ovhal, NirmalKumar Mandal, Shuvankar Mukherjee, TV Anoop, BinodKumar Thakur, L Eswari, JoanFelicita Samson, KrinaBharat Patel, Rajesh Rajagopalan, Sanjeev Gupta, Tejinder Kaur
Abstract
BACKGROUND: Vitiligo is an acquired, idiopathic, and common depigmentation disorder. The values of various epidemiologic parameters are often doubtful due to the methodological weaknesses of the studies. AIMS: To elicit the magnitude of various epidemiological parameters and important correlates of vitiligo. MATERIALS AND METHODS: Every vitiligo patient attending the outpatient department of medical colleges spread over most of the Indian states were examined over a period of 1 year. Various epidemiological and clinical variables were examined and compared with age and sex-matched controls (registered in the Clinical Trial Registry of India CTRI/2017/06/008854). RESULTS: < 0.001, odds ratio (OR) 0.78, 95% confidence interval (CI): 0.71-0.86]. CONCLUSION: This is one of the largest studies done on vitiligo in India. The prevalence of vitiligo was found to be 0.89% among hospital attendees. Prevalence of vitiligo was higher among females than in males and prevalence of family history, consanguinity, hypothyroid disorders were higher in vitiligo than among controls.