Unveiling the role of surface, size, shape and defects of iron oxide nanoparticles for theranostic applications
Geoffrey Cotin, Cristina Blanco-Andujar, Francis Perton, Laura Asín, Jesús M. de la Fuente, Wilfried Reichardt, Denise Schaffner, Dinh-Vu Ngyen, Damien Mertz, Céline Kiefer, Florent Meyer, Simo Spassov, Ovidiu Ersen, Michael Chatzidakis, Gianluigi A. Botton, Céline Henoumont, Sophie Laurent, Jean−Marc Grenèche, Francisco J. Terán, Daniel Ortega, Delphine Felder‐Flesch, Sylvie Bégin‐Colin
Abstract
experiments demonstrated that the magnetic heating capability of octopods occurs especially at low frequencies. The coupling of a small amount of glucose on dendronized octopods succeeded in internalizing them and showing an effect of MH on tumor growth. All measurements evidenced a particular signature of octopods, which is attributed to higher anisotropy, surface effects and/or magnetic field inhomogeneity induced by tips. This approach aiming at an analysis of the structure-property relationships is important to design efficient theranostic nanoparticles.