Fatty Acids Abolish <i>Shigella</i> Virulence by Inhibiting Its Master Regulator, VirF
Rita Trirocco, Martina Pasqua, Angela Tramonti, Milena Grossi, Bianca Colonna, Alessandro Paiardini, Gianni Prosseda
Abstract
In the absence of a valid vaccine, the main therapeutic approach currently used to treat shigellosis is based on the use of antibiotics. The emergence of antibiotic resistance jeopardizes the future effectiveness of this approach.
Topics & Concepts
ShigellosisVirulenceAntibioticsRegulatorShigellaAntibiotic resistanceMicrobiologyBiologyVirologyMedicineBacteriaGeneticsGeneSalmonellaEscherichia coli research studiesViral gastroenteritis research and epidemiologySalmonella and Campylobacter epidemiology