OUP accepted manuscript
Charlotte Buchanan, Huda Mahmoud, Eleanor Cox, Rebecca Noble, Benjamin Prestwich, Isma Kasmi, Maarten W. Taal, Susan Francis, Nicholas M Selby
Abstract
BACKGROUND: Acute kidney injury (AKI) is associated with a marked increase in mortality as well as subsequent chronic kidney disease (CKD) and end-stage kidney disease. We performed multiparametric magnetic resonance imaging (MRI) with the aim of identifying potential non-invasive MRI markers of renal pathophysiology in AKI and during recovery. METHODS: * mapping. RESULTS: * data showed a non-significant trend to increase over time post-AKI. CONCLUSIONS: during AKI and a marked decrease in cortical perfusion. Despite biochemical recovery at 1-year post-AKI, MRI measures indicated persisting abnormalities in some patients. We propose that such patients may be more likely to have further AKI episodes or progress to CKD and further longitudinal studies are required to investigate this. .