Magnesium-L-threonate exhibited a neuroprotective effect against oxidative stress damage in HT22 cells and Alzheimer’s disease mouse model
Ying Xiong, Yuting Ruan, J. Zhao, Yuwen Yang, Liping Chen, Yingren Mai, Qun Yu, Zhiyu Cao, Feifei Liu, Wang Liao, Jun Liu
Abstract
BACKGROUND: -treated HT22 cells and the AD mouse model still remains to be investigated. AIM: , and investigate the mechanism. METHODS: and phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt) pathway proteins was quantified by Western blot. RESULTS: < 0.05). CONCLUSION: -treated HT22 cells and APP/PS1 mice.
Topics & Concepts
Oxidative stressNeuroprotectionViability assayReactive oxygen speciesPharmacologyProtein kinase BChemistryPI3K/AKT/mTOR pathwayApoptosisMedicineBiochemistryMagnesium in Health and DiseaseAluminum toxicity and tolerance in plants and animalsTrace Elements in Health