Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents
Yanlin Jian, Romain Merceron, Steven De Munck, Harriet Forbes, Fabian Hulpia, Martijn Risseeuw, Kristof Van Hecke, Savvas N. Savvides, Hélène Munier‐Lehmann, Helena I. Boshoff, Serge Van Calenbergh
Topics & Concepts
AntimycobacterialChemistryCytotoxicityEnzymeBiochemistryThymidylate synthaseStereochemistryKinaseTuberculosisMycobacterium tuberculosisIn vitroBiologyCancerMedicineGeneticsPathologyFluorouracilBiochemical and Molecular ResearchCancer therapeutics and mechanismsTuberculosis Research and Epidemiology