Ultrasensitive circulating tumor DNA analysis enables precision medicine: experimental workflow considerations
Daniel Andersson, Helena Kristiansson, Mikael Kubista, Anders Ståhlberg
Abstract
. the probability to detect presence of cancer in liquid biopsies, is still an issue. Analysis of multiple mutations in combination with simultaneous assessment of other analytes is one solution. Improved standardization and guidelines will also facilitate the introduction of ctDNA analysis into clinical routine.
Topics & Concepts
Circulating tumor DNAWorkflowPrecision medicineLiquid biopsyCancer biomarkersComputational biologyBiomarker discoveryCancer detectionMinimal residual diseaseBiomarkerPersonalized medicineCancerMedicineComputer scienceBioinformaticsMedical physicsPathologyInternal medicineBiologyProteomicsGeneBone marrowBiochemistryDatabaseCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomicsMolecular Biology Techniques and Applications