Cancer cells evade ferroptosis: sex hormone-driven membrane-bound O-acyltransferase domain-containing 1 and 2 (MBOAT1/2) expression
Alexia Belavgeni, Wulf Tonnus, Andreas Linkermann
Abstract
In a recent manuscript published in Cell , Liang et al. discovered novel ferroptosis regulators, membrane-bound O-acyltransferase domain-containing 1 and 2 (MBOAT1/2). 1 These findings may have implications for ferroptosis-based cancer therapy.
Topics & Concepts
CancerHormoneDomain (mathematical analysis)Cell biologyBiologyCancer researchChemistryBiochemistryGeneticsMathematicsMathematical analysisFerroptosis and cancer prognosisCancer-related molecular mechanisms researchCaveolin-1 and cellular processes