A small molecule inhibitor of the chloride channel TMEM16A blocks vascular smooth muscle contraction and lowers blood pressure in spontaneously hypertensive rats
Onur Çil, Xiaolan Chen, Henry R. Askew Page, Samuel N. Baldwin, Maria C. Jordan, Pyone Myat Thwe, Marc O. Anderson, Peter M. Haggie, Iain A. Greenwood, Kenneth P. Roos, A. S. Verkman
Topics & Concepts
Blood pressureMedicineVascular smooth muscleContraction (grammar)Internal medicineVasoconstrictionSpontaneously hypertensive ratEndocrinologyNifedipineCalciumMesenteric arteriesArterySmooth muscleNitric Oxide and Endothelin EffectsIon Transport and Channel RegulationRenin-Angiotensin System Studies