Electrochemical α-C(sp<sup>3</sup>)–H/O–H cross-coupling of isochromans and alcohols assisted by benzoic acid
Zhuang Wang, Kaikai Niu, Yuxiu Liu, Hongjian Song, Qingmin Wang
Abstract
)-H/O-H cross-coupling reactions of isochromans and alcohols in the presence of benzoic acid, which facilitated the electro-oxidation process and increased the product yield. Various alcohols and isochromans, as well as other structurally similar substrates, gave moderate to high yields of the desired coupling products, and the reaction could be carried out on a gram scale.
Topics & Concepts
Benzoic acidElectrochemistryChemistryAlkoxy groupCoupling reactionMedicinal chemistryCoupling (piping)Organic chemistryElectrodeCatalysisMaterials sciencePhysical chemistryAlkylMetallurgyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions