Targeting mTOR for fighting diseases: A revisited review of mTOR inhibitors
Tian Xu, Dejuan Sun, Yi Chen, Liang Ouyang
Topics & Concepts
PI3K/AKT/mTOR pathwayKinaseRPTORSignal transductionDiscovery and development of mTOR inhibitorsmTORC2ChemistryMechanistic target of rapamycinmTORC1PhosphorylationCancer researchCell biologyBiologyBiochemistryPI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase SignalingCancer Mechanisms and Therapy