Targeting proinsulin to local immune cells using an intradermal microneedle delivery system; a potential antigen-specific immunotherapy for type 1 diabetes
Farah Arikat, Stephanie Hanna, Ravinder Singh, Luciano Vilela, F. Susan Wong, Colin Dayan, Sion Coulman, James C. Birchall
Topics & Concepts
ProinsulinImmune systemImmunologyImmunotherapyAntigenPopulationMedicineCD8Diabetes mellitusEndocrinologyEnvironmental healthAdvancements in Transdermal Drug DeliveryTransgenic Plants and ApplicationsDermatology and Skin Diseases