Without a trace: multiple knockout of CHO host cell hydrolases to prevent polysorbate degradation in biologics
Linus Weiß, Nikolas Zeh, Melanie Maier, Dániel Lakatos, Kerstin Otte, Simon Fischer
Topics & Concepts
PolysorbateChemistryDegradation (telecommunications)TRACE (psycholinguistics)Chinese hamster ovary cellHost (biology)BiochemistryBiologyComputer scienceReceptorPulmonary surfactantGeneticsLinguisticsPhilosophyTelecommunicationsViral Infectious Diseases and Gene Expression in InsectsProtein purification and stabilityVirus-based gene therapy research