Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease

Raaj S. Mehta, Jared R. Mayers, Yancong Zhang, Amrisha Bhosle, Nathaniel R. Glasser, Long H. Nguyen, Wenjie Ma, Sena Bae, Tobyn Branck, Kijun Song, Luke Sebastian, Julián Ávila-Pacheco, Hyuk‐Soo Seo, Clary B. Clish, Sirano Dhe‐Paganon, Ashwin N. Ananthakrishnan, Eric A. Franzosa, Emily P. Balskus, Andrew T. Chan, Curtis Huttenhower