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Mitophagy inhibitor liensinine suppresses doxorubicin-induced cardiotoxicity through inhibition of Drp1-mediated maladaptive mitochondrial fission

Xinyue Liang, Shuyi Wang, Lifeng Wang, Aslı F. Ceylan, Jun Ren, Yingmei Zhang

2020Pharmacological Research156 citationsDOI

Topics & Concepts

MitophagyMitochondrial fissionCardiotoxicityApoptosisMitochondrionPharmacologyCell biologyChemistryBiologyMedicineBiochemistryInternal medicineToxicityAutophagyAutophagy in Disease and TherapyATP Synthase and ATPases ResearchChemotherapy-induced cardiotoxicity and mitigation
Mitophagy inhibitor liensinine suppresses doxorubicin-induced cardiotoxicity through inhibition of Drp1-mediated maladaptive mitochondrial fission | Litcius