The oxygenated products of cryptotanshinone by biotransformation with Cunninghamella elegans exerting anti-neuroinflammatory effects by inhibiting TLR 4-mediated MAPK signaling pathway
Jingshuai Wu, Qinyu Meng, Xiaohui Shi, Lu-Xin Liu, Zhenkun Zhang, Huashi Guan, Chang‐Lun Shao, Chang‐Yun Wang
Topics & Concepts
ChemistryMAPK/ERK pathwaySalvia miltiorrhizap38 mitogen-activated protein kinasesSignal transductionNitric oxideKinaseLipopolysaccharideBiochemistryBiologyTraditional Chinese medicineOrganic chemistryPathologyMedicineEndocrinologyAlternative medicineTraditional Chinese Medicine AnalysisNeuroinflammation and Neurodegeneration MechanismsImmune Response and Inflammation