Litcius/Paper detail

Multitrait Bayesian shrinkage and variable selection models with the BGLR-R package

Paulino Pérez‐Rodríguez, Gustavo de los Campos

2022Genetics76 citationsDOIOpen Access PDF

Abstract

The BGLR-R package implements various types of single-trait shrinkage/variable selection Bayesian regressions. The package was first released in 2014, since then it has become a software very often used in genomic studies. We recently develop functionality for multitrait models. The implementation allows users to include an arbitrary number of random-effects terms. For each set of predictors, users can choose diffuse, Gaussian, and Gaussian-spike-slab multivariate priors. Unlike other software packages for multitrait genomic regressions, BGLR offers many specifications for (co)variance parameters (unstructured, diagonal, factor analytic, and recursive). Samples from the posterior distribution of the models implemented in the multitrait function are generated using a Gibbs sampler, which is implemented by combining code written in the R and C programming languages. In this article, we provide an overview of the models and methods implemented BGLR's multitrait function, present examples that illustrate the use of the package, and benchmark the performance of the software.

Topics & Concepts

Computer scienceSoftwareBenchmark (surveying)Prior probabilityBayesian probabilityGibbs samplingR packageMultivariate statisticsSet (abstract data type)Selection (genetic algorithm)Data miningStatisticsMachine learningArtificial intelligenceMathematicsProgramming languageGeographyGeodesyGenetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and AnimalsGenetics and Plant Breeding
Multitrait Bayesian shrinkage and variable selection models with the BGLR-R package | Litcius