p-CREB and p-DARPP-32 orchestrating the modulatory role of cAMP/PKA signaling pathway enhanced by Roflumilast in rotenone-induced Parkinson's disease in rats
Reham M. Essam, Esraa A. Kandil
Topics & Concepts
CREBRotenoneNeuroprotectionDopaminergicCyclic adenosine monophosphateRoflumilastDopamineRolipramPharmacologyProtein kinase AParkinson's diseaseChemistryPhosphodiesteraseEndocrinologyBiologyInternal medicineMedicineKinaseCell biologyTranscription factorBiochemistryReceptorDiseaseEnzymeMitochondrionGeneCOPDPhosphodiesterase function and regulationCholinesterase and Neurodegenerative DiseasesParkinson's Disease Mechanisms and Treatments