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Advantages of brain penetrating inhibitors of kynurenine-3-monooxygenase for treatment of neurodegenerative diseases

Shaowei Zhang, Mary E.W. Collier, Derren J. Heyes, Flaviano Giorgini, Nigel S. Scrutton

2020Archives of Biochemistry and Biophysics23 citationsDOIOpen Access PDF

Topics & Concepts

Kynurenine pathwayKynurenineKynurenic acidPharmacologyProdrugDiseaseNeuroprotectionCentral nervous systemChemistryNeuroscienceMedicineBiologyBiochemistryTryptophanInternal medicineAmino acidTryptophan and brain disordersBipolar Disorder and TreatmentStress Responses and Cortisol
Advantages of brain penetrating inhibitors of kynurenine-3-monooxygenase for treatment of neurodegenerative diseases | Litcius