Wild-Type Transthyretin Amyloidosis in Female Patients ― Consideration of Sex Differences ―
Yuri Ochi, Toru Kubo, Yuichi Baba, Kenta Sugiura, Motoko Ueda, Kazuya Miyagawa, Tatsuya Noguchi, Takayoshi Hirota, Tomoyuki Hamada, Naohito Yamasaki, Hiroaki Kitaoka
Abstract
This study suggests that a relatively large proportion of elderly females have ATTRwt. Female ATTRwt patients had HF symptoms even at the stage of mild LV hypertrophy and preserved EF. Abdominal fat biopsy may be useful to diagnose ATTRwt, especially in female patients with HF.
Topics & Concepts
TransthyretinAmyloidosisType (biology)Internal medicineMedicineBiologyEcologyAmyloidosis: Diagnosis, Treatment, OutcomesParathyroid Disorders and TreatmentsIon channel regulation and function