Adherence to a MIND-Like Dietary Pattern, Long-Term Exposure to Fine Particulate Matter Air Pollution, and MRI-Based Measures of Brain Volume: The Women’s Health Initiative Memory Study-MRI
Cheng Chen, Kathleen M. Hayden, Joel D. Kaufman, Mark A. Espeland, Eric A. Whitsel, Marc L. Serre, William Vizuete, Tonya Orchard, Xinhui Wang, Helena C. Chui, Mary E. D’Alton, Jiu‐Chiuan Chen, Ka Kahe
Abstract
BACKGROUND: have not been investigated. OBJECTIVES: exposure and lower white matter volume (WMV) differed between women whose usual diet during the last 3 months before baseline was more or less consistent with a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND)-like diet, a dietary pattern that may slow neurodegenerative changes. METHODS: exposure prior to MRI was estimated using geocoded participant addresses and a spatiotemporal model. RESULTS: were not significantly different for women with high MIND scores and women with low MIND scores. DISCUSSION: exposure was associated with lower MRI-based WMV, an indication of brain aging, only among women whose usual diet was less consistent with the MIND-like dietary pattern at baseline. https://doi.org/10.1289/EHP8036.