<scp>Metal‐Free Visible‐Light‐Induced Atom‐Transfer</scp> Radical Addition Reaction of Alkenes/Alkynes with <scp>ICH<sub>2</sub>CN</scp>
Chunxiang Pan, Yunyan Meng, Yao Deng, Bingjie Zhou, Jingchao Chen, Zhenxiu He, Weiqing Sun, Ruhima Khan, Baomin Fan
Abstract
Comprehensive Summary New blue‐light promoted methods for the addition of iodoacetonitrile (ICH 2 CN) to alkene/alkynes have been developed. The reaction led to the formation of cyanoalkylated products when conjugated alkene/styrene was used. In the case of alkynes and non‐conjugated alkenes, iodoalkylation takes place furnishing the corresponding alkenyl iodides and alkyl iodides, respectively. Notably, trans ‐alkenyl iodides were obtained as the major product. A plausible reaction mechanism is also proposed.
Topics & Concepts
ChemistryAlkeneStyreneConjugated systemAlkylPhotochemistryAlkyneAtom (system on chip)Medicinal chemistryMetalOrganic chemistryCatalysisCopolymerPolymerComputer scienceEmbedded systemRadical Photochemical ReactionsOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization Methods