Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types
Sadiq Umar, Karol Palasiewicz, Michael V. Volin, Bianca Romay, Rani Rahat, Chandana Tetali, Shiva Arami, Mónica Gumá, Christian Ascoli, Nadera Sweiss, Ryan K. Zomorrodi, Luke O'neill, Shiva Shahrara
Topics & Concepts
GlycolysisProtein kinase BOxidative phosphorylationCell biologyCancer researchPentose phosphate pathwayChemistryBiologySignal transductionBiochemistryMetabolismImmune cells in cancerPhagocytosis and Immune RegulationImmune Cell Function and Interaction