R-(−)-ketamine modifies behavioral effects of morphine predicting efficacy as a novel therapy for opioid use disorder1
Jeffrey M. Witkin, Jay Kranzler, Kyle Kaniecki, Piotr Popik, Jodi L. Smith, Kenji Hashimoto, Jonathan Sporn
Topics & Concepts
KetamineAnhedoniaDysphoriaAddictionMorphineSubstance abuseConditioned place preferenceMedicinePhysical dependencePsychologyOpioidClinical psychologyPsychiatryPharmacologySchizophrenia (object-oriented programming)Internal medicineAnxietyReceptorTreatment of Major DepressionTryptophan and brain disordersNeuroscience and Neuropharmacology Research